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  • About Femur Fractures

    The femur is one of the strongest bones in the body. The incidence of femur fractures that have occurred without trauma is quite significant. The bones are becoming very brittle and weak and are easily fracturing. Fosamax was designed to help make the bones stronger not have the opposite effect. Patients taking this medication for long periods of time, the test results showed a low bone turnover. This can mean greater accumulated micro-damage in the bone, making some patients more susceptible to fractures.

    The fractures that occurred were low-energy fractures. This happened when patients fell from a standing position. The bone cracks were in a horizontal pattern. The patients were on a long-term therapy to help prevent osteoporosis. Many were also taking Fosamax for over 7 years.

    Fosamax is a drug prescribed to help treat and prevent osteoporosis, a condition in which the bones become thin and weak and easily broken. Fosamax is a bisphosphonate which is in a class of drugs to help increase bone mass. Fosamax helps reduce fractures in patients that have osteoporosis. While Fosamax is supposed to make bones stronger, recent evidence suggests that some patients who Fosamax for more than 5 years could have spontaneous fractures.

    In 2008, the Food and Drug Administration spoke to the Merck Company who manufacturers Fosamax. They spoke to them in regards to reports of the femur fractures. Merck has since added reports of possible femur fractures to their list of side effects, which is included in their drug package insert.

    On October 13, 2010, the Food and Drug Administration called for a revision on Fosamax’s warning label that said the “Risk of atypical fractures of the femur in patients who take bisphosphonates for osteoporosis” have been linked to patients who take bisphosphonates, such as Fosamax.

    On March 20, 2010, the New England Journal of Medicine published a study that found patients taking Fosamax for longer periods of time, had a high rate of femur fractures. The study’s authors came to the conclusion that Fosamax slows the development of new collagen in the bone, causing its users to become more prone to bone fractures.

    On February 23, 2011, the Journal of the American Medical Association published a study suggesting that taking bisphosphonates, such as Fosamax, can nearly triple the risk of femur fractures in patients that have taken this drug for over 5 years.

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