Proton Pump Inhibitor (PPI) medications are used to control stomach acid and manage symptoms related to health conditions such as heart burn, acid reflux, and indigestion. These medications are some of the most common used in the world today.
Despite the popularity of PPI medications, there are indications these medications might not be entirely safe. Several studies show users experienced heart health issues, including heart attacks, after using PPI medications.
Now there is also evidence that PPI medication use could also be linked to kidney health issues. Two separate studies indicate users face an increased risk for developing chronic kidney disease (CKD).
A study published in the February 2016 issues of the Journal of American Medical Association showed PPI medications might increase the risk for chronic kidney disease by as much as 50%.
Another study was presented at the 2015 American Society of Nephrology meeting and showed similar results. Some researchers believe PPI medications create serious damage to the kidneys when patients repeatedly suffer from acute interstitial nephritis, which is linked to short-term use of the medications.
There is also evidence PPIs reduce levels of magnesium in the blood. Insufficient magnesium is linked to kidney damage.
PPI medications are available by prescription and in over-the-counter dosages. Before using either product you should consult with your doctor about the potential risk.
Brand name prescription PPI medications include:
PPI medication use puts patients at risk for a variety of serious complications in addition to CKD and heart attack, including:
- Bone fractures
- Increase the risk of various kidney events, including acute kidney injury and an inflammatory kidney disease known as acute interstitial nephritis.
- Acquired infections
- Potential birth defects